Predictors of community-acquired pneumonia in patients with acute decompensated heart failure: the results of the analysis of the hospital sample EPOHA-D-CHF


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Abstract

Community-acquired pneumonia is a significant factor leading to acute decompensated heart failure (ADHF). Each subsequent decompensation of the patient with heart failure leads to decrease in the functional reserve of the myocardium and worsens the life prognosis of this patient. Aim. Identify the most significant predictors of community-acquired pneumonia and their im-pact on the risk of this disease in patients with ADHF. Materials and methods. The analysis of the hospital sample of patients (n=852) with ADHF. In 16.5% of hospitalizations, community-acquired pneumonia was found. Results. The presence of symmetrical rales in the lungs, hepatomegaly, left ventricular failure signs, dilated cardiomyopathy, hypotension are increasing the risk of pneumonia in 3.7 (p<0.001), 1.6 (p=0.02), 1.86 (p=0.005), 1.72 (p=0.002), 2.7 (p=0.003) times. Conclusion. Based on results of a single and multivariate regression analysis, the risk of pneumonia is statistically significant increase in patients with acute left ventricular failure, dilated cardiomyopathy, hypotension, with signs of stagnation in the small and large circulatory circles. Different combinations of these predictors were found in 80% of patients with ADHF, among which in 20% of cases there was a combination of 3-5 factors.

About the authors

D S Polyakov

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

к.м.н., ассистент каф. внутренних болезней Nizhny Novgorod, Russia

I V Fomin

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

Email: nzs-nn@yandex.ru
д.м.н., проф. каф. внутренних болезней Nizhny Novgorod, Russia

A R Vaisberg

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

к.м.н., доц. каф. внутренних болезней Nizhny Novgorod, Russia

F Yu Valikulova

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

к.м.н., доц. каф. внутренних болезней Nizhny Novgorod, Russia

E Yu Ivanchenko

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

к.м.н., доц. каф. внутренних болезней Nizhny Novgorod, Russia

N Kraiem

Nizhny Novgorod State Medical Academy Ministry of Health of Russia

аспирант каф. внутренних болезней Nizhny Novgorod, Russia

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