Ferrous sulfate in the treatment of iron deficiency anemia: The positions continue


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Abstract

The paper discusses treatment strategy and tactics for iron deficiency anemia. It gives data on the comparative efficacy of different iron sulfate drugs, their bioavailability, effects on peroxidation processes, and side effects. The paper also considers the clinical significance of a dosage form of iron-containing drugs with a sustained iron release, as well as ways to reduce the frequency and magnitude of side effects when ferrous sulfate is used.

About the authors

L I Dvoretsky

ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России

Москва, Россия

References

  1. WHO. Iron deficiency anemia; assesment, prevention and control. A guide for programme managers. Geneva: World Health Organization, 2001:1-114
  2. Румянцев А.Г., Масчан А.А. Федеральные клинические рекомендации по диагностике и лечению железодефицитной анемии. М., 2014.
  3. Auerbach M, Adamson J. How we diagnose and treat iron deficiency anemia. Am J Hematol. 2016;91(1):31-38. https://doi.org/10.1002/ajh.24201
  4. Дворецкий Л. И., Заспа Е. А. Алгоритмы диагностики и лечения железодефицитных анемий. Фарматека 2006;5(120): 117-120.
  5. Дворецкий Л.И., Колендо С.Е. Сорбифер Дурулес в лечении железодефицитных анемий. Международный медицинский журнал 1999;3-4.
  6. Городецкий В.В., Годулян О.В., Верткин А.Л. Сравнительная эффективность и переносимость различных железосодержащих препаратов у больных железодефицитной анемией. Русский медицинский журнал, 2004;5:309-315.
  7. Стуклов Н.И. Железодефицитная анемия в практике гинеколога. Алгоритмы диагностики, профилактики и лечения. Акушерство и гинекология. 2016;7:99-104. https://doi.org/10.18565/aig
  8. Дворецкий Л.И., Ивлева О.В. Ключевые вопросы лечения железодефицитной анемии. Врач. 2017;2:68-73.
  9. Okam M, Koch A, Tran M. Iron deficiency anemia treatment response to oral iron therapy: a pooled analysis of five randomized controlled trials. Haematologica. 2015;100:xxx. https://doi.org/10.3324/haematol.2015.129114
  10. Isler M, Delibas N, Guclu M, Gultekin F, Sutcu R, Bahceci M, Kosar A.Superoxide dismutase and glutathione peroxidase in erytrocytes of patient with iron deficieny anemia: effects of different treatment modalities. Croatian medical journal. 2002;43(1):16-19.
  11. Kurtoglu E, Ugor A, Baltaci A, Undar L. Effect of iron supplementation on oxidative stress and antioxidant status in iron deficiency anemia. Biol Trace Elem Res. 2003;96(1-3):117-124. https://doi.org/10.1385/bter
  12. Дворецкий Л.И., Заспа Е.А., Литвицкий П.Ф., Болевич С.Б., Меньшова Н.И. Свободнорадикальные процессы у больных железодефицитной анемией на фоне лечения препаратами железа. Терапевтический архив. 2006;78(1):52-57.
  13. Aly S, Fayed M, Ahmed S, Abdella A, Tamam A, Mohmmed N. Effects of oral iron (ferrous versus ferric) supplementation on oxidative stress and antioxidant status in pregnant women with iron deficiency: controlled trial. Egypt J Haematol. 2016;41(2):31-41. https://doi.org/10.4103/1110-1067.186392
  14. Tiwari A, Mahdi A, Chandyan S, Zahra F, Godbole M, Jaiswar S, Srivastava V, Negi M. Oral iron supplementation leads to oxidative imbalance in anemic women: a prospective study. Clin Nutr. 2011;30(2):188-193. https://doi.org/10.1016/j.clnu.2010.08.001
  15. Tolkien Z, Stecher L, Mander A, Pereira D, Powell J. Ferrous sulfate supplementation causes significant gastrointestina side-effects in adults: a systematic review and meta-analysis. PLoS One. 2015;10(2): e0117383. https://doi.org/10.1371/journal.pone.0117383
  16. Громова О.А. Нежелательные эффекты сульфата железа в акушерской, педиатрической и терапевтической практике. Земский врач. 2010;2:1-8.
  17. Cheney K, Gumbiner C, Benson B, Tenenbein M.Survival after a severe iron poisoning treated with intermittent infusions of deferoxamine. J Toxicol Clin Toxicol. 1995;33(1):61-66. https://doi.org/10.3109/15563659509020217
  18. Назаренко О.А. Громова О.А., Демидов В.И., Торшин И.Ю., Томилова И. К., Алексахина Е.Л. Сравнительная оценка хронической перегрузки железом при применении препаратов железа в субтоксических дозах. Фарматека. 2016;18:40-44.
  19. Geisser P, Burckhardt S. The Pharmacokinetics and Pharmacodynamics of Iron Preparations. Pharmaceutics. 2011;3(1):12-33. https://doi.org/10.3390/pharmaceutics3010012
  20. Kaye P, Abdulla K, Wood J, James P, Foley S, Ragunath K, Atherton J. Iron-induced mucosal pathology of the upper gastrointestinal tract: a common finding in patients on oral iron therapy. Histopathology. 2008;53(3):311-317. https://doi.org/10.1111/j.1365-2559.2008.03081.x
  21. Marginean E, Bennick M, Cyczk J, Robert M, Jain D. Gastric siderosis: patterns and significance. Am J Surg Pathol. 2006;30(4):514-520. https://doi.org/10.1097/00000478-200604000-00013
  22. Hallberg L, Ryttinger L, Sölvell L.Side-effects of oral iron therapy. A double-blind study of different iron compounds in tablet form. Acta Med Scand Suppl. 1966;180(S459):3-10. https://doi.org/10.1111/j.0954-6820.1966.tb19403.x
  23. Cancelo-Hidalgo M, Castelo-Branco C, Palacios S, Haya-Palazuelos J, Ciria-Recasens M, Manasanch J, Pérez-Edo L.Tolerability of different oral iron supplements: a systematic review. Curr Med Res Opin. 2013;29(4):291-303. https://doi.org/10.1185/03007995.2012.761599
  24. McDiarmid T, Johnson Diane E. Are any oral iron formulations better tolerated than ferrous sulfate? J Fam Pract. 2002;51(6):575-577.
  25. Rybo G, Sölvell L. Side-effect studies on a new sustained release iron preparation. Scandinavian Journal of Haematology. 1971;8(4):257-264. https://doi.org/10.1111/j.1600-0609.1971.tb00873.x
  26. Elwood P, Williams G. Comparative trial of slow-release and conventional iron preparations. Practitioner. 1970;204(224):812-815.
  27. Brock C, Curry H, Hanna C. Adverse effects of iron supplementation: a comparative trial of a wax-matrix iron preparation and conventional ferrous sulfate tablets. Clinical Therapeutics. 1985; 7(5):568-573.
  28. Manasanch J, Castelo-Branco C, Cancelo-Hidalgo M. Tolerability of different oral iron supplements: a systematic review. In: Proceedings of the 16th Wonca European Conference; 2010.
  29. Стуклов Н.И., Семенова Е.Н. Лечение железодефицитной анемии. Что важнее, эффективность или переносимость? Существует ли оптимальное решение? Журнал международной медицины. 2013;1(2):47-55.
  30. Low M, Speedy J, Styles C, De-Regil L, Pasricha S.. Daily iron supplementation for improving anaemia, iron status and health in menstruating women. Cochrane Database Syst Rev. 2016; 18;4:CD009747. https://doi.org/10.1002/14651858.CD009747.pub2
  31. Schrier S. So you know how to treat iron deficiency anemia. Blood. 2015;126(17):1971-1971. https://doi.org/10.1182/blood-2015-09-666511
  32. Moretti D, Goede J, Zeder C. et al. Oral iron supplements increase hepcidin and decrease iron absorption from daily or twice-daily doses in iron-depleted young women Blood. 2015;126 (17):1981-1989. https://doi.org/10.1182/blood-2015-05-642223
  33. Rüegg P. When less is really more ETH Zurich 2015; /https://www.ethz.ch/en/news.../iron-supplementation.htm).
  34. Rimon E, Kagansky N, Kagansky M, Mechnick L, Mashiah T, Namir M, Levy S.Are we giving too much iron? Low-dose iron therapy is effective in octogenarians. Am J Med. 2005;118 (10):1142-1147. https://doi.org/10.1016/j.amjmed.2005.01.065
  35. Brise H. Influence of meals on iron absorption in oral iron therapy. Acta Med Scanda Suppl. 1962;171(S376):39-45. https://doi.org/10.1111/j.0954-6820.1962.tb18681.x
  36. Российский фармацевтический рынок: итоги и прогнозы. Ремедиум. Итоги 2016 года. 2017:145.
  37. Santiago P. Ferrous versus ferric oral iron formulations for the treatment of iron deficiency: a clinical overview. Scientific World Journal. 2012;2012:846824. https://doi.org/10.1100/2012/846824
  38. Стуклов Н.И., Семенова Е.Н. Железодефицитная анемия. Современная тактика диагностики и лечения, критерии эффективности терапии. Клиническая медицина. 2013;12(61-67).

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