Protein-losing enteropathy
- Authors: Parfenov AI1, Krums LM1
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Affiliations:
- Московский клинический научно-практический центр ДЗМ
- Issue: Vol 89, No 2 (2017)
- Pages: 4-9
- Section: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/32144
- DOI: https://doi.org/10.17116/terarkh20178924-9
- ID: 32144
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Abstract
Protein-losing enteropathy (PLE) is a rare complication of intestinal diseases. Its main manifestation is hypoproteinemic edema. The diagnosis of PLE is based on the verification of protein loss into the intestinal lumen, by determining fecal α1-antitrypsin concentration and clearance. The localization of the affected colonic segment is clarified using radiologic and endoscopic techniques. The mainstay of treatment for PLE is a fat-free diet enriched with medium-chain triglycerides. Surgical resection of the affected segment of the colon may be the treatment of choice for severe hypoproteinemia resistant to drug therapy.
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##article.viewOnOriginalSite##About the authors
A I Parfenov
Московский клинический научно-практический центр ДЗММосква, Россия
L M Krums
Московский клинический научно-практический центр ДЗММосква, Россия
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