Therapy of acute massive blood loss in a hemophiliac male: case report

Andrey Yul'evich Bulanov; Буланов Андрей Юльевич; Elena Markovna Shulutko; Шулутко Елена Марковна; Evgeniy Evgen'evich Karpov; Карпов Евгений Евгеньевич; Tat'yana Yur'evna Polyanskaya; Полянская Татьяна Юрьевна; Georgiy Vladimirovich Mishin; Мишин Георгий Владимирович; Sergey Aleksandrovich Morozov; Морозов Сергей Александрович; Nikolay Nikolaevich Kalinin; Калинин Николай Николаевич; Aleksandr Vladimirovich Tochenov; Точенов Александр Владимирович; Konstantin Vladimirovich Yatskov; Яцков Константин Владимирович; Vladimir Yur'evich Zorenko; Зоренко Владимир Юрьевич; Magomed Sultanovich Sampiev; Сампиев Магомед Султанович; A Yu Bulanov; Bulanov A Yu; E M Shulutko; Shulutko E M; E E Karpov; Karpov E E; T Yu Polyanskaya; Polyanskaya T Yu; G V Mishin; Mishin G V; S A Morozov; Morozov S A; N N Kalinin; Kalinin N N; A V Tochenov; Tochenov A V; K V Yatskov; Yatskov K V; V Yu Zorenko; Zorenko V Yu; M S Sampiev; Sampiev M S

Therapy of acute massive blood loss in a hemophiliac male: case report

Authors: Bulanov A.Y.¹, Shulutko E.M.¹, Karpov E.E.¹, Polyanskaya T.Y.¹, Mishin G.V.¹, Morozov S.A.¹, Kalinin N.N.¹, Tochenov A.V.¹, Yatskov K.V.¹, Zorenko V.Y.¹, Sampiev M.S.¹, Bulanov AY.², Shulutko EM², Karpov EE², Polyanskaya TY.², Mishin GV², Morozov SA², Kalinin NN², Tochenov AV², Yatskov KV², Zorenko VY.², Sampiev MS²
Affiliations:
1. ФГБУ Гематологический научный центр Минздравсоцразвития РФ
2. Hematological Research Center, Moscow
Issue: Vol 83, No 8 (2011)
Pages: 70-73
Section: Editorial
URL: https://journals.rcsi.science/0040-3660/article/view/30923
ID: 30923

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Abstract

A case is reported of management of massive intraoperative blood loss in a male patient with severe hemophilia. Extirpation of hip pseudotumor with one-stage osteosynthesis with an intramedullary joint-pin in a 43 year old male patient was accompanied with 7.5 l blood loss. The infusion-transfusion therapy (ITT) contained transfusion media about 1/3 of the total volume, fresh-frozen plasma and erythrocyte-containing media were used 1:1. Infusion solutions consisted of balanced polyelectrolytic solutions, hydroxyethylated starches 130/0.4, hyperchaes. Intraoperative normovolemic hemodilution and reinfusion of wound blood were made (CellSaver). ITT target markers were standard hemodynamics control tests. Hemostasis monitoring was conducted with thromboelastography. Complex ITT based on modern principles of clinical transfusiology provided a complete and safe compensation of massive intraoperative blood loss in a patient with severe hemophilia.

Keywords

massive blood loss, hemophilia, infusion-transfusion therapy, thromboelastography

References

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Therapy of acute massive blood loss in a hemophiliac male: case report

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