电邮这篇文章 Echocardiography - prognosis of the course of infectious endocarditisand long-term survival in this disease
- 作者: Maslov SV1, Lobanov MY.1, Kovalev Y.R1
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隶属关系:
- Санкт-Петербургская государственная педиатрическая медицинская академия
- 期: 卷 79, 编号 12 (2004)
- 页面: 44-48
- 栏目: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/29951
- ID: 29951
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Aim. To determine prognostic opportunities of echocardiography (ECG) in infectious endocarditis (IE)
basing on the assessment of microbial vegetations size and degree of valvular failure.
Material and methods. Of 114 patients with definite IE (72 male, 42 female), 90 ones had primary
and 24 secondary endocarditis. The prospective study included all the survivors in the IE active stage -78 patients.
Results. Vegetations > 1 cm in size were detected in 50.8%patients, < 1 cm - in 49.2%. Hospital lethality
in vegetations > 1 cm and < 1 cm was 25.8 and 16.1%, respectively. Thromboembolism rate
was 81 and 64.2%, respectively. One-year survival was 78.7 and 71.4%, two-year survival 66.5 and
61.7%, three-year survival 66.5 and 49.4%, five-year survival - 51.7 and 32.9% in vegetations < 1
cm and > 1 cm, respectively. Valvular regurgitation of the first degree was in 17.5%, of the second degree - in 41.9%,
thirdfourth degree - in 36.6% patients. Hospital lethality in mitral valve failure
was 32.1%, in aortic and tricuspid failure - 17.8 and 11.4%, respectively.
Conclusion. EchoCG was most effective for predicting thromboembolism and cardiac failure. Valvular
regurgitation of the third-fourth degree significantly correlates with severe cardiac failure. ECG is less
informative for predicting hospital lethality.
basing on the assessment of microbial vegetations size and degree of valvular failure.
Material and methods. Of 114 patients with definite IE (72 male, 42 female), 90 ones had primary
and 24 secondary endocarditis. The prospective study included all the survivors in the IE active stage -78 patients.
Results. Vegetations > 1 cm in size were detected in 50.8%patients, < 1 cm - in 49.2%. Hospital lethality
in vegetations > 1 cm and < 1 cm was 25.8 and 16.1%, respectively. Thromboembolism rate
was 81 and 64.2%, respectively. One-year survival was 78.7 and 71.4%, two-year survival 66.5 and
61.7%, three-year survival 66.5 and 49.4%, five-year survival - 51.7 and 32.9% in vegetations < 1
cm and > 1 cm, respectively. Valvular regurgitation of the first degree was in 17.5%, of the second degree - in 41.9%,
thirdfourth degree - in 36.6% patients. Hospital lethality in mitral valve failure
was 32.1%, in aortic and tricuspid failure - 17.8 and 11.4%, respectively.
Conclusion. EchoCG was most effective for predicting thromboembolism and cardiac failure. Valvular
regurgitation of the third-fourth degree significantly correlates with severe cardiac failure. ECG is less
informative for predicting hospital lethality.
作者简介
S Maslov
Санкт-Петербургская государственная педиатрическая медицинская академияСанкт-Петербургская государственная педиатрическая медицинская академия
M Lobanov
Санкт-Петербургская государственная педиатрическая медицинская академияСанкт-Петербургская государственная педиатрическая медицинская академия
Yu Kovalev
Санкт-Петербургская государственная педиатрическая медицинская академияСанкт-Петербургская государственная педиатрическая медицинская академия
参考
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- Mugge A. Echocardiography detection of cardiac valve vegetations and prognostic implications. Infect. Dis. Clin. N. Arr 1993; 7(4): 877-898.
- Гланц С. Медико-биологическая статистика. М.: Практика; 1999.
- Маслов С. В., Кцоева Т. В., Ковалев Ю. Р. Инфекционньп эндокардит клапанов левых камер сердца у инъекционны: наркоманов. Клин. мед. 2002; 3: 23-28.
- Демин А. А., Дробышева В. П., Семенова Ю. В. Прогностическое значение эхокардиографии при инфекционном эндокардите. Клин. мед. 2002; 4: 34-37.
- Jaffe W. М., Morgan D. E., Pearlman A. S., Otto С. М. Infective endocarditis, 1983-1988: echocardiographic findings anc factors influencing morbidity and mortality. J. Am. Coll. Cardiol. 1990; 15(6): 1227-1237.
- Mugge A., Daniel W. C., Frank G., Lichtlen P. R. Echocardiography in infective endocarditis: reassessment of prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach. J. Am. Coll. Cardiol. 1989;14(3): 631-638.
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