Email this article Features of the upper gastrointestinal tract mucous membrane state in patients with atherosclerosis of the mesenteric arteries
- Authors: Selyanina A.A.1, Dolgushina A.I.1, Kusnezowa A.S.1, Genkel V.V.1, Olevskaya E.R.1,2, Nikushkina K.V.1, Khikhlova A.O.2
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Affiliations:
- South Ural State Medical University
- Chelyabinsk Regional Clinical Hospital
- Issue: Vol 95, No 2 (2023)
- Pages: 152-157
- Section: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/132899
- DOI: https://doi.org/10.26442/00403660.2023.02.202058
- ID: 132899
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Abstract
Aim. To evaluate the clinical and endoscopic features of diseases of the upper gastrointestinal tract (GIT) in patients with atherosclerosis of the mesenteric arteries (MA).
Materials and methods. The study included 48 patients with atherosclerosis of MA and 43 patients without atherosclerosis of MA, who were hospitalized in the department of vascular surgery of the Chelyabinsk Regional Clinical Hospital in the period from 2019 to 2021. All patients underwent multispiral computed tomoangiography of the visceral and lower limb arteries, esophagogastroduodenoscopy.
Results. Assessment of lesions of the upper gastrointestinal tract revealed a higher incidence of erosive and ulcerative gastroduodenopathies among patients with atherosclerosis of MA (60.4%), compared with patients without atherosclerosis MA (39.5%); p=0.047. Signs of severe atrophy according to the data of histological examination were statistically significantly more frequent among patients with atherosclerosis of MA (29.2 and 11.6%; p=0.031). According to the results of logistic regression, the following predictors of erosions and ulcers of the upper gastrointestinal tract were revealed: the severity of stenosis of the superior mesenteric artery (SMA) is more than 35%, the body mass index (BMI) is less than 25.9 and the total score on the HADS scale is more than 6.5 points for depression (p=0.008).
Conclusion. Erosive-ulcerative gastroduodenopathies and atrophy of the gastric mucosa are significantly more common in the group of patients with MA atherosclerosis. The main risk factors for erosions and ulcers of the upper gastrointestinal tract in patients with MA atherosclerosis are: the severity of SMA stenosis is more than 35%, a decrease in BMI is less than 25.9 and an increase in the HADS score is more than 6.5 points.
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##article.viewOnOriginalSite##About the authors
Anna A. Selyanina
South Ural State Medical University
Author for correspondence.
Email: anna-selyanina@mail.ru
ORCID iD: 0000-0002-3481-8092
ассистент каф. госпитальной терапии
Russian Federation, ChelyabinskAnastasia I. Dolgushina
South Ural State Medical University
Email: dolgushinaai@yandex.ru
ORCID iD: 0000-0003-2569-1699
д-р мед. наук, доц., зав. каф. госпитальной терапии
Russian Federation, ChelyabinskAlla S. Kusnezowa
South Ural State Medical University
Email: kuzja321@mail.ru
ORCID iD: 0000-0002-0357-5702
канд. мед. наук, доц. каф. госпитальной терапии
Russian Federation, ChelyabinskVadim V. Genkel
South Ural State Medical University
Email: henkel-07@mail.ru
ORCID iD: 0000-0001-5902-3803
канд. мед. наук, доц. каф. пропедевтики внутренних болезней
Russian Federation, ChelyabinskElena R. Olevskaya
South Ural State Medical University; Chelyabinsk Regional Clinical Hospital
Email: endo74@mail.ru
ORCID iD: 0000-0002-7385-8505
д-р мед. наук, доц., проф. каф. госпитальной хирургии, зав. отд-нием эндоскопии
Russian Federation, Chelyabinsk; ChelyabinskKarina V. Nikushkina
South Ural State Medical University
Email: knikushkina81@gmail.com
ORCID iD: 0000-0002-3900-9278
канд. мед. наук, вед. науч. сотр. Научно-исследовательского института иммунологии
Russian Federation, ChelyabinskAlina O. Khikhlova
Chelyabinsk Regional Clinical Hospital
Email: alina_hihlova@mail.ru
ORCID iD: 0000-0001-6444-4573
врач-эндоскопист отд-ния эндоскопии
Russian Federation, ChelyabinskReferences
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