Diagnostic and treatment difficulties in kidney damage in the patient with generalized sarcoidosis during COVID-19. Case report

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Abstract

The presented clinical observation reflects the difficulties of differential diagnosis of progressive kidney damage in a patient with sarcoidosis who has undergone a new coronavirus infection. The differential circle included interstitial nephritis as an exacerbation of the underlying disease, acute drug-induced kidney injury, acute glomerulonephritis. Nephrobiopsy confirmed the diagnosis of acute sarcoid tubulointerstitial nephritis with acute tubular necrosis. Timely administration of corticosteroids led to the control of the sarcoidosis process, restoration of kidney function.

About the authors

Marina V. Lebedeva

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: lebedeva_m_v_2@staff.sechenov.ru
ORCID iD: 0000-0002-5923-1837

доц. каф. внутренних, профессиональных болезней и ревматологии

Russian Federation, Moscow

Natalia V. Chebotareva

Sechenov First Moscow State Medical University (Sechenov University)

Email: lebedeva_m_v_2@staff.sechenov.ru
ORCID iD: 0000-0003-2128-8560

д-р мед. наук, проф. каф. внутренних, профессиональных болезней и ревматологии

Russian Federation, Moscow

Vladimir D. Beketov

Sechenov First Moscow State Medical University (Sechenov University)

Email: lebedeva_m_v_2@staff.sechenov.ru
ORCID iD: 0000-0002-6377-0630

ассистент каф. внутренних, профессиональных болезней и ревматологии

Russian Federation, Moscow

References

  1. Baughman RP, Lower EE, Buchanan M, et al. Risk and outcome of COVID-19 infection in sarcoidosis patients: results of a self-reporting questionnaire. Sarcoidosis Vasc Diffuse Lung Dis. 2020;37(4):e2020009. doi: 10.36141/svdld.v37i4.10726
  2. Baughman RP, Lower EE. COVID-19 infections in sarcoidosis: a prospective single center study of 886 sarcoidosis patients. Sarcoidosis Vasc Diffuse Lung Dis. 2021;38(2):e2021029. doi: 10.36141/svdld.v38i2.11646
  3. Brito-Zerón P, Gracia-Tello B, Robles A, et al. Characterization and Outcomes of SARS-CoV-2 Infection in Patients with Sarcoidosis. Viruses. 2021;13(6):1000. doi: 10.3390/v13061000
  4. Chebotareva N, Berns S, Berns A, et al. Acute kidney injury and mortality in coronavirus disease 2019: results from a cohort study of 1,280 patients. Kidney Res Clin Pract. 2021;40(2):241-9. doi: 10.23876/j.krcp.20.128

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