Iontophoretic transport of associates based on porous Keplerate-type cluster polyoxometalate Mo72Fe30 and containing biologically active substances


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The possibility of iontophoretic transport through the native membranes of biologically active substances (vitamin B1 and insulin) associated with porous clusters Mo72Fe30 polyoxometalate of the Keplerate type is demonstrated for the first time in an experimental setup. The diffusion coefficient is estimated. The possibility of transferring Keplerate ions with a protective coating of biocompatible polymer polyvinylpyrrolidone is also shown.

作者简介

A. Ostroushko

Research Institute of Physics and Applied Mathematics

编辑信件的主要联系方式.
Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002

I. Gagarin

Research Institute of Physics and Applied Mathematics

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002

M. Tonkushina

Research Institute of Physics and Applied Mathematics

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002

K. Grzhegorzhevskii

Research Institute of Physics and Applied Mathematics

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002

I. Danilova

Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002; Yekaterinburg, 620049

I. Gette

Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620002; Yekaterinburg, 620049

G. Kim

Postovsky Institute of Organic Synthesis, Ural Branch

Email: alexander.ostroushko@urfu.ru
俄罗斯联邦, Yekaterinburg, 620990


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