Intermolecular interactions in rifabutin–2-hydroxypropyl-β-cyclodextrin–water solutions, according to solubility data
- 作者: Anshakova A.1,2, Vinogradov E.3, Sedush N.4, Kurtikyan T.5, Zhokhov S.6, Polshakov V.6, Ermolenko Y.1,2, Konyukhov V.2, Maksimenko O.1, Gelperin S.1
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隶属关系:
- Nanosystem LTD
- Mendeleev University of Chemical Technology
- National Research Council
- National Research Centre “Kurchatov Institute,”
- Molecular Structure Research Center
- Department of Chemistry
- 期: 卷 90, 编号 5 (2016)
- 页面: 983-989
- 栏目: Physical Chemistry of Solutions
- URL: https://journals.rcsi.science/0036-0244/article/view/168168
- DOI: https://doi.org/10.1134/S0036024416050058
- ID: 168168
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详细
The formulations of rifabutin (RB) and 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), obtained using different preparation techniques, are studied by means of differential scanning calorimetry and molecular spectroscopy (FTIR, NMR, Raman scattering, and photon correlation light scattering). It is established that molecules of RB do not form inclusion complexes with the molecules of HP-β-CD, and an increase in the solubility of RB determined earlier is caused by the formation of weak intermolecular associates.
作者简介
A. Anshakova
Nanosystem LTD; Mendeleev University of Chemical Technology
编辑信件的主要联系方式.
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 115193; Moscow, 125047
E. Vinogradov
National Research Council
Email: anshakova_a@mail.ru
加拿大, Ottawa, ON, K1A 0R6
N. Sedush
National Research Centre “Kurchatov Institute,”
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 123098
T. Kurtikyan
Molecular Structure Research Center
Email: anshakova_a@mail.ru
亚美尼亚, Yerevan, 0014
S. Zhokhov
Department of Chemistry
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 119991
V. Polshakov
Department of Chemistry
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 119991
Yu. Ermolenko
Nanosystem LTD; Mendeleev University of Chemical Technology
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 115193; Moscow, 125047
V. Konyukhov
Mendeleev University of Chemical Technology
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 125047
O. Maksimenko
Nanosystem LTD
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 115193
S. Gelperin
Nanosystem LTD
Email: anshakova_a@mail.ru
俄罗斯联邦, Moscow, 115193