Iontophoretic transport of associates based on porous Keplerate-type cluster polyoxometalate Mo72Fe30 and containing biologically active substances
- Авторы: Ostroushko A.1, Gagarin I.1, Tonkushina M.1, Grzhegorzhevskii K.1, Danilova I.1,2, Gette I.1,2, Kim G.3
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Учреждения:
- Research Institute of Physics and Applied Mathematics
- Institute of Immunology and Physiology, Ural Branch
- Postovsky Institute of Organic Synthesis, Ural Branch
- Выпуск: Том 91, № 9 (2017)
- Страницы: 1811-1815
- Раздел: Colloid Chemistry and Electrochemistry
- URL: https://journals.rcsi.science/0036-0244/article/view/169708
- DOI: https://doi.org/10.1134/S0036024417090230
- ID: 169708
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Аннотация
The possibility of iontophoretic transport through the native membranes of biologically active substances (vitamin B1 and insulin) associated with porous clusters Mo72Fe30 polyoxometalate of the Keplerate type is demonstrated for the first time in an experimental setup. The diffusion coefficient is estimated. The possibility of transferring Keplerate ions with a protective coating of biocompatible polymer polyvinylpyrrolidone is also shown.
Об авторах
A. Ostroushko
Research Institute of Physics and Applied Mathematics
Автор, ответственный за переписку.
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002
I. Gagarin
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002
M. Tonkushina
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002
K. Grzhegorzhevskii
Research Institute of Physics and Applied Mathematics
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002
I. Danilova
Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002; Yekaterinburg, 620049
I. Gette
Research Institute of Physics and Applied Mathematics; Institute of Immunology and Physiology, Ural Branch
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620002; Yekaterinburg, 620049
G. Kim
Postovsky Institute of Organic Synthesis, Ural Branch
Email: alexander.ostroushko@urfu.ru
Россия, Yekaterinburg, 620990