Email this article Association Constants in the Bovine Serum Albumin/Human Serum Albumin–Tween 20 System in Aqueous Solutions
- Authors: Vlasova I.M.1,2, Vlasov A.A.1, Grapendaal G.R.1, Saletskii A.M.1
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Affiliations:
- Faculty of Physics
- Center for Theoretical Problems of Physicochemical Pharmacology
- Issue: Vol 92, No 4 (2018)
- Pages: 714-718
- Section: Physical Chemistry of Solutions
- URL: https://journals.rcsi.science/0036-0244/article/view/169963
- DOI: https://doi.org/10.1134/S0036024418040325
- ID: 169963
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Abstract
The association constants in the bovine serum albumin/human serum albumin–Tween 20 system are determined in aqueous solutions at pH 3.5–8.0 by means of nonpolarized fluorescence and protein fluorescence quenching. It is found that the most efficient association of serum albumin molecules with Tween 20 micelles occurs at pH 5.0 near the isoelectric points of proteins.
About the authors
I. M. Vlasova
Faculty of Physics; Center for Theoretical Problems of Physicochemical Pharmacology
Email: vlasovairina1979@mail.ru
Russian Federation, Moscow, 119991; Moscow, 119991
A. A. Vlasov
Faculty of Physics
Author for correspondence.
Email: vlasovairina1979@mail.ru
Russian Federation, Moscow, 119991
G. R. Grapendaal
Faculty of Physics
Email: vlasovairina1979@mail.ru
Russian Federation, Moscow, 119991
A. M. Saletskii
Faculty of Physics
Email: vlasovairina1979@mail.ru
Russian Federation, Moscow, 119991
