Role of the Nucleolus in Rearrangements of the IGH Locus
- Авторлар: Iarovaia O.V.1,2,3, Ioudinkova E.S.1,2,3, Razin S.V.1,2,4, Vassetzky Y.S.2,4,3
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Мекемелер:
- Institute of Gene Biology
- LIA1066 “Laboratoire franco-russe de recherche en oncologie”
- CNRS UMR8126, Universite Paris Sud 11, Institut de Cancerologie Gustave Roussy
- Biological Faculty
- Шығарылым: Том 52, № 2 (2018)
- Беттер: 182-189
- Бөлім: Reviews
- URL: https://journals.rcsi.science/0026-8933/article/view/163451
- DOI: https://doi.org/10.1134/S0026893317050211
- ID: 163451
Дәйексөз келтіру
Аннотация
The review summarizes the results from a series of studies focusing on the role that the nucleolus plays in maturation of the IGH locus and the choice of its partner genes in leukemia-associated translocations. The role of nuclear compartmentalization and nuclear localization of translocated oncogenes in ectopic activation of their transcription is discussed.
Авторлар туралы
O. Iarovaia
Institute of Gene Biology; LIA1066 “Laboratoire franco-russe de recherche en oncologie”; CNRS UMR8126, Universite Paris Sud 11, Institut de Cancerologie Gustave Roussy
Хат алмасуға жауапты Автор.
Email: iarovaia@inbox.ru
Ресей, Moscow, 119334; Villejuif; Villejuif, F-94805
E. Ioudinkova
Institute of Gene Biology; LIA1066 “Laboratoire franco-russe de recherche en oncologie”; CNRS UMR8126, Universite Paris Sud 11, Institut de Cancerologie Gustave Roussy
Email: iarovaia@inbox.ru
Ресей, Moscow, 119334; Villejuif; Villejuif, F-94805
S. Razin
Institute of Gene Biology; LIA1066 “Laboratoire franco-russe de recherche en oncologie”; Biological Faculty
Email: iarovaia@inbox.ru
Ресей, Moscow, 119334; Villejuif; Moscow, 119991
Y. Vassetzky
LIA1066 “Laboratoire franco-russe de recherche en oncologie”; Biological Faculty; CNRS UMR8126, Universite Paris Sud 11, Institut de Cancerologie Gustave Roussy
Email: iarovaia@inbox.ru
Франция, Villejuif; Moscow, 119991; Villejuif, F-94805
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