Азафилоновые пигменты грибов как перспективные натуральные красители

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Аннотация

Микроскопические грибы образуют и экскретируют многочисленные и разнообразные вторичные метаболиты, в том числе пигменты различной окраски, которые могут быть использованы как альтернатива применяемым в промышленности химическим и растительным красителям. Одним из перспективных классов грибных пигментов являются азафилоновые соединения, впервые обнаруженные у грибов рода Monascus. В обзоре дан анализ публикаций по образованию пигментов азафилонового типа у грибов Monascus, а также у Talaromyces и Aspergillus сavernicola. Приведены краткие сведения об антимикробной, противоопухолевой, противовоспалительной и гиполипидемической активностях азафилоновых пигментов. Обсуждены возможные стратегии повышения производительности процесса получения, а также направленного синтеза желтых, оранжевых и красных пигментов и их производных. В целом обзор позволяет оценить важность азафилоновых пигментов, перспективы и пути расширения их производства для применения в качестве натуральных красителей в различных областях.

Об авторах

Т. В. Антипова

Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина
Российской академии наук – обособленное подразделение ФГБУН ФИЦ
“Пущинский научный центр биологических исследований РАН”

Автор, ответственный за переписку.
Email: tantipova@ibpm.pushchino.ru
Россия, 142290, Пущино

В. П. Желифонова

Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина
Российской академии наук – обособленное подразделение ФГБУН ФИЦ
“Пущинский научный центр биологических исследований РАН”

Email: tantipova@ibpm.pushchino.ru
Россия, 142290, Пущино

К. В. Зайцев

Московский государственный университет им. М.В. Ломоносова

Email: tantipova@ibpm.pushchino.ru
Россия, 119234, Москва

М. Б. Вайнштейн

Институт биохимии и физиологии микроорганизмов им. Г.К. Скрябина
Российской академии наук – обособленное подразделение ФГБУН ФИЦ
“Пущинский научный центр биологических исследований РАН”

Email: tantipova@ibpm.pushchino.ru
Россия, 142290, Пущино

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