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Effect of silver nanoclusters on the copper resistance of Achromobacter insolitus LCu2
- Authors: Burygin G.L.1,2,3, Astankova A.S.1,2, Chumakov D.S.1, Kryuchkova Y.V.1,3
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Affiliations:
- Saratov Scientific Centre of the Russian Academy of Sciences
- Saratov State University
- Saratov State University of Genetics, Biotechnology, and Engineering named after N.I. Vavilov
- Issue: Vol 94, No 2 (2025)
- Pages: 195–198
- Section: SHORT COMMUNICATIONS
- URL: https://journals.rcsi.science/0026-3656/article/view/291521
- DOI: https://doi.org/10.31857/S0026365625020081
- ID: 291521
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Abstract
Abstract. In this work, the resistance of Achromobacter insolitus LCu2 cells to copper (II) was reduced by adding 1 μM silver nanoclusters to the culture medium: the maximum tolerable concentration decreased by 4 times, the minimum inhibitory concentration – by 25 times. It is assumed that nanoclusters disrupt the functioning of the copper (II) efflux system through binding to the CusC protein, which leads to a partial loss of the ability of bacteria to export excess copper (II) cations from cells.
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About the authors
G. L. Burygin
Saratov Scientific Centre of the Russian Academy of Sciences; Saratov State University; Saratov State University of Genetics, Biotechnology, and Engineering named after N.I. Vavilov
Author for correspondence.
Email: burygingl@gmail.com
Institute of Biochemistry and Physiology of Plants and Microorganisms
Russian Federation, Saratov, 410049; Saratov, 410012; Saratov, 410012A. S. Astankova
Saratov Scientific Centre of the Russian Academy of Sciences; Saratov State University
Email: burygingl@gmail.com
Institute of Biochemistry and Physiology of Plants and Microorganisms
Russian Federation, Saratov, 410049; Saratov, 410012D. S. Chumakov
Saratov Scientific Centre of the Russian Academy of Sciences
Email: burygingl@gmail.com
Institute of Biochemistry and Physiology of Plants and Microorganisms
Russian Federation, Saratov, 410049Y. V. Kryuchkova
Saratov Scientific Centre of the Russian Academy of Sciences; Saratov State University of Genetics, Biotechnology, and Engineering named after N.I. Vavilov
Email: burygingl@gmail.com
Institute of Biochemistry and Physiology of Plants and Microorganisms
Russian Federation, Saratov, 410049; Saratov, 410012References
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