Email this article Effect of Ascorbic Acid Isomeric Forms on Antibacterial Activity of Its Chitosan Salts
- Authors: Gegel’ N.O.1, Zudina I.V.2, Malinkina O.N.2, Shipovskaya A.B.2
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Affiliations:
- Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences
- Chernyshevsky Saratov State University
- Issue: Vol 87, No 5 (2018)
- Pages: 732-737
- Section: Experimental Articles
- URL: https://journals.rcsi.science/0026-2617/article/view/163717
- DOI: https://doi.org/10.1134/S0026261718050107
- ID: 163717
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Abstract
Optical rotatory dispersion studies revealed water solutions of chitosan in L- and D-ascorbic acid to exhibit right rotation with anomalous dispersion and left rotation with normal dispersion, respectively. Microbiological investigation and transmission electron microscopy revealed the chitosan salt with D-ascorbic acid to cause deeper destructive changes than pure chitosan, which resulted in higher antibacterial activity against Staphylococcus aureus 209P and Escherichia coli 113-13.
Keywords
About the authors
N. O. Gegel’
Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences
Author for correspondence.
Email: gegelno@yandex.ru
Russian Federation, Saratov
I. V. Zudina
Chernyshevsky Saratov State University
Email: gegelno@yandex.ru
Russian Federation, Saratov
O. N. Malinkina
Chernyshevsky Saratov State University
Email: gegelno@yandex.ru
Russian Federation, Saratov
A. B. Shipovskaya
Chernyshevsky Saratov State University
Email: gegelno@yandex.ru
Russian Federation, Saratov
