Experimental study of areas of increased nitrogen monoxide generation for an autonomous life support system

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

Background: Nitric oxide NO is used in medicine and as an additive in artificial atmospheres for boxes and incubators. It is mainly obtained by a plasma method, passing a gas discharge through air or a mixture of nitrogen and oxygen. The use of effective conditions for obtaining this gas will optimize the design of the device and increase the NO yield while maintaining the input power.

Aim: Evaluation and analysis of the influence of pulse repetition frequency on the amount of nitrogen monoxide produced in the discharge.

Methods: To experimentally evaluate the effect of pulse repetition frequency on the change in the amount of NO obtained, an experiment was conducted for which a test bench was assembled based on a plasma chemical reactor (PCR) and an OPTIMA 7 gas analyzer, which was used to record NO concentration values corresponding to a given pulse repetition frequency.

Results: As a result of the work carried out, the existence of regions in which the concentrations of nitrogen mono- and dioxide change according to a nonlinear law was demonstrated, presumably associated with the resonant characteristics of the PCR parts, including the dependence of the reactive and active resistance on the PCR design.

Conclusion: The analysis and calculations revealed that the evaporation surface area directly impacts the amount of evaporated boil-off gas and the power consumption of the boil-off gas compressor. The data obtained suggest the possibility of creating low-power life support systems, such as incubators, as well as closed-loop therapeutic treatment rooms based on a device for generating NO.

About the authors

Artemiy G. Kuznetsov

Bauman Moscow State Technical University

Author for correspondence.
Email: kuznetsovag@bmstu.ru
ORCID iD: 0009-0000-7721-2333
SPIN-code: 8202-9812
Russian Federation, 5 2nd Baumanskaya st, bldg 1, Moscow, 105005

Nikolay A. Sharapov

Bauman Moscow State Technical University

Email: nash1257@yandex.ru
ORCID iD: 0000-0002-6374-4942

Cand. Sci. (Engineering), Associate Professor

Russian Federation, 5 2nd Baumanskaya st, bldg 1, Moscow, 105005

Vladimir A. Voronov

Bauman Moscow State Technical University

Email: breads@mail.ru
ORCID iD: 0000-0001-8581-9936
SPIN-code: 4502-9590

Cand. Sci. (Engineering), Associate Professor

Russian Federation, 5 2nd Baumanskaya st, bldg 1, Moscow, 105005

References

  1. Sun P, Pan J, Tian Y, et al. Teeth whitening with hydrogen peroxide using cold atmospheric pressure DC microjet air plasma. IEEE Trans Plasma Sci. 2010;38(8):1897–1904.
  2. Vasil’eva TM. Obtaining bioactive compounds and materials based on processes that stimulate beam-plasma effects on matter [dissertation abstract]. Moscow; 2016. (In Russ.) EDN: CGWETQ
  3. Ghaffari A, Neil DH, Ardakani A, et al. A direct delivery system for nitric oxide gas for bacterial and mammalian cell cultures. Nitric Oxide. 2005;12(3):129–140. doi: 10.1016/j.niox.2005.01.003
  4. Vanin AF. Nitric oxide is a universal regulator of biological processes. In: NO-therapy: theoretical aspects, practical experience and problems of using nitric oxide in medicine: collected materials of a scientific-practical conference. Moscow; 2001:22–27. (In Russ.)
  5. Lichtenberg M, Line L, Schrameyer V, et al. Nitric oxide-mediated oxygen release in anoxic. Pseudomonas aeruginosa. iScience. 2021;24(12):103404. doi: 10.1016/j.isci.2021.103404 PMCID: PMC8608891
  6. Rahmanto JS, Kalinowski DS, Lane DJR, et al. Nitrogen monoxide (NO) storage and transport by dinitrosyl-dithiol-iron complexes: long-lived NO that is trafficked by interacting proteins. J Biol Chem. 2012;287(10):6960–6968. doi: 10.1074/jbc.M111.306936
  7. Chen Y, Guo Q, Wei J, et al. Inhibitory effect and mechanism of nitric oxide (NO) fumigation on fungal diseases of Xinjiang-Saimaiti dried apricots. LWT. 2019;116:108500. doi: 10.1016/j.lwt.2019.108500
  8. Enemark JH, Feltham RD. Stereochemical control of valence and its application to the reduction of coordinated NO and N₂. Proc Natl Acad Sci U S A. 1972;69(12):3534–3536. doi: 10.1073/pnas.69.12.3534
  9. Ghaffari A, Neil DH, Ardakani A, et al. Direct delivery system for nitric oxide gas for bacterial and mammalian cell cultures. Nitric Oxide. 2005;12(3):129–140.
  10. Nie X, Zhang H, Shi X, et al. Asiatic nitric oxide gel accelerates the healing of diabetic skin ulcers by activating the Wnt/β-catenin signaling pathway. Int Immunopharmacol. 2020;79:106109. doi: 10.1016/j.intimp.2019.106109
  11. Sharapov NA, Chukanov VI, Distanov RR, et al. Research of an air plasma-chemical reactor for a new medical device. Eng J Sci Innov. 2013;10. (In Russ.)
  12. O’Meara C, Timpa J, Peek G, et al. Nitric Oxide on Extracorporeal Life Support: Circuit Modifications for a Safe Therapy. J Extra Corpor Technol. 2022;54(2):142–147. doi: 10.1051/ject/202254142 EDN: ZKPKHL
  13. Kuznetsov AG, Sharapov NA. On the influence of the properties of the resonant discharge circuit on the parameters of a plasma-chemical reactor. In: XLVIII Academic Readings on Cosmonautics: Collection of abstracts dedicated to the memory of Academician S.P. Korolev and other outstanding Russian scientists – pioneers of space exploration. Moscow: BMSTU; 2024:374–376. (In Russ.) EDN: ETMJHA
  14. Zeldovich YB. Oxidation of nitrogen during combustion and explosions. Acta Physicochim URSS. 1946;21(4):577–628. (In Russ.)
  15. Lavoie GA, Heywood JB, Keck JC. Experimental and theoretical study of nitric oxide formation in internal combustion engines. Combust Sci Technol. 1970;1(4):313–326. doi: 10.1080/00102206908952211
  16. Kuhn S, Bibinov N, Gesche R, Awakowicz P. High-frequency non-thermal atmospheric pressure plasma source: generation of nitric oxide and ozone for biomedical applications. Plasma Sources Sci Technol. 2010;19(1):015013. doi: 10.1088/0963-0252/19/1/015013 EDN: MYSRDP
  17. Um HS, Na YH, Choi EH, Cho G. Dissociation and excitation coefficients of nitrogen molecules and the formation of nitrogen monoxide. Phys Plasmas. 2013;20(8):083502. doi: 10.1063/1.4817805
  18. Qi Y, Hu X, Wei W, et al. Basic plasma-chemical process of arc discharge nitric oxide production. Plasma Sci Technol. 2011;13(6):702–707. doi: 10.1088/1009-0630/13/6/13
  19. Suris AL. Plasma-Chemical Processes and Apparatuses. Moscow: Khimiia; 1989. (In Russ.)
  20. Suris AL. On the problem of calculation of plasma-chemical reactors. Izv Sib Otd Akad Nauk SSSR Ser Tekh Nauk. 1978;1(3):16–20. (In Russ.)
  21. Polak LS, Ovsiannikov AA, Slovetskii DI, Vurzel’ FB. Theoretical and Applied Plasma Chemistry. Moscow: Nauka; 1975. (In Russ.)
  22. Kuznetsov AG. Study of the possibility of creating a low-power device for regeneration of the breathing mixture. In: Student Scientific Spring: Collection of abstracts of the All-Russian student conference dedicated to the 110th anniversary of the birth of Academician V.N. Chelomey. Moscow: Nauchnaia Biblioteka; 2024:637–639. (In Russ.) EDN: HYFNTK
  23. Distanov RR, Dusalieva RR, Egorova AA, et al. Calorimetric study of the energy balance of a plasma-chemical reactor. In: IX International Symposium on Radiation-Plasma Dynamics: collection of scientific papers. Moscow; 2012:272–276. (In Russ.)

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2025 Eco-Vector

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).