Radiolytic Inactivation of Ponceau 4R Mutagenicity in Aqueous Solution

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Abstract

The electron-beam treatment of an aqueous solution of the azo dye Ponceau 4R (0.02 g/dm3) at a dose of 1.5 kGy in air led to the complete elimination of color and genotoxicity. The addition of OH radicals to the system of conjugated bonds of the dye (the formation of OH adducts) was a key radiolytic process, which led to the elimination of side groups with lower binding energies

About the authors

A. V. Ponomarev

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: ponomarev@ipc.rssi.ru
Moscow, 119071 Russia

E. M. Kholodkova

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences

Email: ponomarev@ipc.rssi.ru
Moscow, 119071 Russia

I. V. Zotova

St. Petersburg State University; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences

Email: ponomarev@ipc.rssi.ru
St. Petersburg, 199034 Russia; St. Petersburg, 199034 Russia

A. R. Shumega

St. Petersburg State University

Email: ponomarev@ipc.rssi.ru
St. Petersburg, 199034 Russia

E. I. Stepchenkova

St. Petersburg State University; Vavilov Institute of General Genetics, St. Petersburg Branch, Russian Academy of Sciences

Author for correspondence.
Email: ponomarev@ipc.rssi.ru
St. Petersburg, 199034 Russia; St. Petersburg, 199034 Russia

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Copyright (c) 2023 А.В. Пономарев, Е.М. Холодкова, И.В. Зотова, А.Р. Шумега, Е.И. Степченкова

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