Molecular Basis of Cardioprotection in Ischemic Heart Disease
- Авторлар: Shemarova I.1, Nesterov V.1
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Мекемелер:
- Sechenov Institute of Evolutionary Physiology and Biochemistry
- Шығарылым: Том 55, № 3 (2019)
- Беттер: 163-173
- Бөлім: Reviews
- URL: https://journals.rcsi.science/0022-0930/article/view/159721
- DOI: https://doi.org/10.1134/S0022093019030013
- ID: 159721
Дәйексөз келтіру
Аннотация
The review addresses the mechanisms of adaptation of cardiomyocytes to hypoxia and ischemia and analyzes the signaling mechanisms responsible for expression of metabolic genes and the formation of tolerance to hypoxia and ischemia with a special focus on the role of HIF-1α, succinate, and ATP-dependent K+-channels (KATP-channels) in the regulation of adaptive responses of cardiomyocytes during myocardial ischemia.
Негізгі сөздер
Авторлар туралы
I. Shemarova
Sechenov Institute of Evolutionary Physiology and Biochemistry
Хат алмасуға жауапты Автор.
Email: irina-shemarova@yandex.ru
Ресей, St. Petersburg
V. Nesterov
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: irina-shemarova@yandex.ru
Ресей, St. Petersburg