Age-Dependent Activity of Lactate Dehydrogenase in Brain Structures during Postnatal Ontogenesis of Rats Exposed to Hypoxia in the Fetal Period

A. M. Rashidova; U. F. Gashimova

doi:10.1134/S0022093019030049

Age-Dependent Activity of Lactate Dehydrogenase in Brain Structures during Postnatal Ontogenesis of Rats Exposed to Hypoxia in the Fetal Period

Authors: Rashidova A.M.¹, Gashimova U.F.¹
Affiliations:
1. Abdulla Garayev Institute of Physiology
Issue: Vol 55, No 3 (2019)
Pages: 191-197
Section: Comparative and Ontogenic Biochemistry
URL: https://journals.rcsi.science/0022-0930/article/view/159730
DOI: https://doi.org/10.1134/S0022093019030049
ID: 159730

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Abstract

This study deals with the dynamics of lactate dehydrogenase (LDG) activity in brain structures during early postnatal ontogenesis (days 17 and 30) and the reproductive period (day 90) of white rats exposed to hypoxia in the fetal period of prenatal ontogenesis (days 18-20). It was established that in rats that underwent prenatal hypoxia in the fetal period the level of LDG activity did not reach its control values with age during postnatal ontogenesis. In most cases, hypoxia led to increase LDG activity in the brain structures.