Evolutionary Aspects of Cardioprotection

Аннотация

The review addresses the mechanisms of adaptation of the myocardium and cells of the cardiovascular system to hypoxia and ischemia as well as biochemical mechanisms of cardioprotection in animals of different phylogenetic levels. A special focus is placed on general adaptive strategies developed by evolutionarily distant animals in response to hypoxia and ischemia and on preconditioning and myocardial hibernation phenomena.