Involvement of Ca2+ in the development of ischemic disorders of myocardial contractile function


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Abstract

The review addresses the role of Ca2+ ions in the development of ischemic disorders of myocardial contractility associated with changes in Ca2+ homeostasis in cardiomyocytes and mitochondrial Ca2+ overload. A special attention is paid to the analysis of intracellular signaling mechanisms activated during the development of ischemic and reperfusion injury of the myocardium.

About the authors

I. V. Shemarova

Sechenov Institute of Evolutionary Physiology and Biochemistry

Author for correspondence.
Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg

V. P. Nesterov

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg

S. M. Korotkov

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg

K. V. Sobol’

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg

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