Involvement of Ca2+ in the development of ischemic disorders of myocardial contractile function
- Authors: Shemarova I.V.1, Nesterov V.P.1, Korotkov S.M.1, Sobol’ K.V.1
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Affiliations:
- Sechenov Institute of Evolutionary Physiology and Biochemistry
- Issue: Vol 53, No 5 (2017)
- Pages: 368-379
- Section: Reviews
- URL: https://journals.rcsi.science/0022-0930/article/view/159323
- DOI: https://doi.org/10.1134/S0022093017050027
- ID: 159323
Cite item
Abstract
The review addresses the role of Ca2+ ions in the development of ischemic disorders of myocardial contractility associated with changes in Ca2+ homeostasis in cardiomyocytes and mitochondrial Ca2+ overload. A special attention is paid to the analysis of intracellular signaling mechanisms activated during the development of ischemic and reperfusion injury of the myocardium.
About the authors
I. V. Shemarova
Sechenov Institute of Evolutionary Physiology and Biochemistry
Author for correspondence.
Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg
V. P. Nesterov
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg
S. M. Korotkov
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg
K. V. Sobol’
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: irina-shemarova@yandex.ru
Russian Federation, St. Petersburg