Determination of 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid in water by capillary electrophoresis with direct spectrophotometric detection

Abstract

An approach for determining 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid (decomposition products of such blister agent as lewisite) in water by capillary zone electrophoresis was proposed. The conditions of determination such as the wavelength and mode of detection, the composition of running buffer solution, the injection volume, and the program for conditioning the capillary were optimized. The developed method is characterized by high accuracy, reproducibility, selectivity, and the absence of interfering effects of the matrix of natural water. The method was used to analyze various water samples, and the accuracy was confirmed by the “added-found” technique. The limits of detection of 2-chlorovinylarsonous acid and 2-chlorovinylarsonic acid in water samples were determined by direct spectrophotometric detection at λ = 195 nm to be 0.3 and 0.5 mg L^–1, respectively.