Email this article Implants for Reconstructive Surgery Based on Electrospun Poly(3-hydroxybutyrate) Fibers
- Authors: Ol’khov A.A.1,2, Akatov V.S.3, Prosvirin A.A.4, Staroverova O.V.5, Filatov Y.N.6, Gol’dshtrakh M.A.7, Iordanskii A.L.5
-
Affiliations:
- G. V. Plekhanov Russian University of Economics
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- A. I. Evdokimov Moscow State University of Medicine and Dentistry
- N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
- L. Ya. Karpov Research Institute of Physical Chemistry
- Ministry of Finance of the Russian Federation, Gokhran of Russia
- Issue: Vol 49, No 3 (2017)
- Pages: 222-226
- Section: Article
- URL: https://journals.rcsi.science/0015-0541/article/view/235012
- DOI: https://doi.org/10.1007/s10692-017-9872-0
- ID: 235012
Cite item
Open Access
Access granted
Subscription Access
Abstract
Nonwoven microfibrous materials based on poly(3-hydroxybutyrate) (PHB) were produced by electrospinning. The fiber supramolecular structure was investigated using DSC and EPR. It was shown that the PHB fiber consisted of perfect and less perfect crystallites with an amorphous phase that combined regions of different density. A model of an artificial implant for reconstructive surgery was developed based on a nonwoven fibrous PHB matrix with the required physicomechanical characteristics, high biocompatibility, and the optimal morphology for growth of cell cultures and increased implant regenerative capability.
About the authors
A. A. Ol’khov
G. V. Plekhanov Russian University of Economics; N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Author for correspondence.
Email: aolkhov72@yandex.ru
Russian Federation, Moscow; Moscow
V. S. Akatov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Russian Federation, Pushchino, Moscow Oblast
A. A. Prosvirin
A. I. Evdokimov Moscow State University of Medicine and Dentistry
Email: aolkhov72@yandex.ru
Russian Federation, Moscow
O. V. Staroverova
N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Russian Federation, Moscow
Yu. N. Filatov
L. Ya. Karpov Research Institute of Physical Chemistry
Email: aolkhov72@yandex.ru
Russian Federation, Moscow
M. A. Gol’dshtrakh
Ministry of Finance of the Russian Federation, Gokhran of Russia
Email: aolkhov72@yandex.ru
Russian Federation, Moscow
A. L. Iordanskii
N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Russian Federation, Moscow
Supplementary files
