Implants for Reconstructive Surgery Based on Electrospun Poly(3-hydroxybutyrate) Fibers
- Autores: Ol’khov A.A.1,2, Akatov V.S.3, Prosvirin A.A.4, Staroverova O.V.5, Filatov Y.N.6, Gol’dshtrakh M.A.7, Iordanskii A.L.5
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Afiliações:
- G. V. Plekhanov Russian University of Economics
- N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- A. I. Evdokimov Moscow State University of Medicine and Dentistry
- N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
- L. Ya. Karpov Research Institute of Physical Chemistry
- Ministry of Finance of the Russian Federation, Gokhran of Russia
- Edição: Volume 49, Nº 3 (2017)
- Páginas: 222-226
- Seção: Article
- URL: https://journals.rcsi.science/0015-0541/article/view/235012
- DOI: https://doi.org/10.1007/s10692-017-9872-0
- ID: 235012
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Resumo
Nonwoven microfibrous materials based on poly(3-hydroxybutyrate) (PHB) were produced by electrospinning. The fiber supramolecular structure was investigated using DSC and EPR. It was shown that the PHB fiber consisted of perfect and less perfect crystallites with an amorphous phase that combined regions of different density. A model of an artificial implant for reconstructive surgery was developed based on a nonwoven fibrous PHB matrix with the required physicomechanical characteristics, high biocompatibility, and the optimal morphology for growth of cell cultures and increased implant regenerative capability.
Sobre autores
A. Ol’khov
G. V. Plekhanov Russian University of Economics; N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Autor responsável pela correspondência
Email: aolkhov72@yandex.ru
Rússia, Moscow; Moscow
V. Akatov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Rússia, Pushchino, Moscow Oblast
A. Prosvirin
A. I. Evdokimov Moscow State University of Medicine and Dentistry
Email: aolkhov72@yandex.ru
Rússia, Moscow
O. Staroverova
N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Rússia, Moscow
Yu. Filatov
L. Ya. Karpov Research Institute of Physical Chemistry
Email: aolkhov72@yandex.ru
Rússia, Moscow
M. Gol’dshtrakh
Ministry of Finance of the Russian Federation, Gokhran of Russia
Email: aolkhov72@yandex.ru
Rússia, Moscow
A. Iordanskii
N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: aolkhov72@yandex.ru
Rússia, Moscow
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