Thermocycle and Evolutionary Combinatorics in the Genesis and Evolution of Protobiopolymers. Basic Kinetic Principles
- Authors: Varfolomeev S.D.1, Tsybenova S.B.1, Bykov V.I.1, Goldberg V.M.1
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Affiliations:
- Emanuel Institute of Biochemical Physics
- Issue: Vol 481, No 2 (2018)
- Pages: 117-120
- Section: Physical Chemistry
- URL: https://journals.rcsi.science/0012-5016/article/view/153895
- DOI: https://doi.org/10.1134/S0012501618080043
- ID: 153895
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Abstract
The basic kinetic principles of genesis and evolution of protobiopolymeric molecules are discussed. An approach combining polymerization and selection of macromolecular structures is the thermocycle providing the thermodynamic feasibility of formation of the monomer–monomer bond and kinetic selection of structures by picking more regular complexes. The basic kinetic principle of the successful evolutionary process is formulated as follows: the systems win if the mechanism of their development involves exponential growth steps.
About the authors
S. D. Varfolomeev
Emanuel Institute of Biochemical Physics
Email: vibykov@mail.ru
Russian Federation, Moscow, 119334
S. B. Tsybenova
Emanuel Institute of Biochemical Physics
Email: vibykov@mail.ru
Russian Federation, Moscow, 119334
V. I. Bykov
Emanuel Institute of Biochemical Physics
Author for correspondence.
Email: vibykov@mail.ru
Russian Federation, Moscow, 119334
V. M. Goldberg
Emanuel Institute of Biochemical Physics
Email: vibykov@mail.ru
Russian Federation, Moscow, 119334
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