Thermocycle and Evolutionary Combinatorics in the Genesis and Evolution of Protobiopolymers. Basic Kinetic Principles


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Abstract

The basic kinetic principles of genesis and evolution of protobiopolymeric molecules are discussed. An approach combining polymerization and selection of macromolecular structures is the thermocycle providing the thermodynamic feasibility of formation of the monomer–monomer bond and kinetic selection of structures by picking more regular complexes. The basic kinetic principle of the successful evolutionary process is formulated as follows: the systems win if the mechanism of their development involves exponential growth steps.

About the authors

S. D. Varfolomeev

Emanuel Institute of Biochemical Physics

Email: vibykov@mail.ru
Russian Federation, Moscow, 119334

S. B. Tsybenova

Emanuel Institute of Biochemical Physics

Email: vibykov@mail.ru
Russian Federation, Moscow, 119334

V. I. Bykov

Emanuel Institute of Biochemical Physics

Author for correspondence.
Email: vibykov@mail.ru
Russian Federation, Moscow, 119334

V. M. Goldberg

Emanuel Institute of Biochemical Physics

Email: vibykov@mail.ru
Russian Federation, Moscow, 119334

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