Cationic Copolymerization of Cholesterol Vinyl Ether with N-Allenylpyrrolidone: A Route to Pharmacologically Promising Oligomers
- Autores: Markova M.1, Tatarinova I.1, Tarasova O.1, Apartsin K.2, Kireeva V.2, Trofimov B.1
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Afiliações:
- Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences
- Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences
- Edição: Volume 485, Nº 2 (2019)
- Páginas: 112-115
- Seção: Chemistry
- URL: https://journals.rcsi.science/0012-5008/article/view/154418
- DOI: https://doi.org/10.1134/S0012500819040037
- ID: 154418
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Resumo
Cationic copolymerization of cholesterol vinyl ether with N-allenylpyrrolidone yielded co-oligomers with molecular mass of 1200–2100. The polymerization of N-allenylpyrrolidone involves both 1,2- and 2,3-positions of the allenyl substituent to give four types of units as a result of prototropic isomerization of the initially formed structures. In the developed method, the composition of co-oligomers can be controlled and, hence, their hydrophilic/hydrophobic balance, solubility, and membranotropic properties can also be contolled to change the potential biological activity of the products.
Sobre autores
M. Markova
Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033
I. Tatarinova
Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033
O. Tarasova
Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033
K. Apartsin
Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033
V. Kireeva
Irkutsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033
B. Trofimov
Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences
Autor responsável pela correspondência
Email: boris_trofimov@irioch.irk.ru
Rússia, Irkutsk, 664033