The Redox Properties and Antiradical Activity of Terpenophenols

Resumo

The redox properties and antiradical activity of terpenophenols (2,6-diisobornyl-4-methylphenol and 3-isocamphyl-2-naphthol) in comparison with BHT (butylhydroxytoluene, 2,6-di-tert-butyl-4-methylphenol) have been studied. The terpenophenols have been shown to react more readily in electron transfer processes as compared with BHT, and they have been found to react with electrochemically generated superoxide radical anion (\({\text{O}}_{2}^{{\centerdot - }}\)). The effect of the compounds on the rate of \({\text{O}}_{2}^{{\centerdot - }}\) generation upon adrenaline oxidation in an alkaline medium and the ability of biopreparations based on Russian sturgeon liver and gonad homogenates to deactivate \({\text{O}}_{2}^{{\centerdot - }}\) have been studied. Adrenaline oxidation inhibition and the increase in superoxide dismutation activity of the biopreparations in the presence of terpenophenols has been shown, and this fact can indicate the ability of these compounds to decrease the probability of oxidative stress enlargement. A correlation has been established between the redox properties and antioxidant activity of terpenophenols in the model system of adrenaline oxidation in the presence of the biopreparations.