New Adamantane Derivatives with NO-Generating Fragment
- 作者: Serkov I.V.1, Proshin A.N.1, Ustinov A.K.1, Lednev B.V.1, Fomina-Ageeva E.V.2, Ashba A.M.2, Bezuglov V.V.2, Bachurin S.O.1
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隶属关系:
- Institute of Physiologically Active Substances
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- 期: 卷 478, 编号 1 (2018)
- 页面: 9-11
- 栏目: Chemistry
- URL: https://journals.rcsi.science/0012-5008/article/view/154164
- DOI: https://doi.org/10.1134/S0012500818010044
- ID: 154164
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详细
An approach to the synthesis of adamantane derivatives with NO-generating fragment containing nitroxy group has been developed. 1-Aminoadamantane, memantine, and adamantanecarboxylic acid have been used as initial compounds. The prepared compounds have shown ability to generate nitric oxide in a system mimicking biological reactions of nitro group reduction.
作者简介
I. Serkov
Institute of Physiologically Active Substances
编辑信件的主要联系方式.
Email: serkoviv@mail.ru
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
A. Proshin
Institute of Physiologically Active Substances
Email: serkoviv@mail.ru
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
A. Ustinov
Institute of Physiologically Active Substances
Email: serkoviv@mail.ru
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
B. Lednev
Institute of Physiologically Active Substances
Email: serkoviv@mail.ru
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
E. Fomina-Ageeva
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: serkoviv@mail.ru
俄罗斯联邦, Moscow, 117997
A. Ashba
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: serkoviv@mail.ru
俄罗斯联邦, Moscow, 117997
V. Bezuglov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: serkoviv@mail.ru
俄罗斯联邦, Moscow, 117997
S. Bachurin
Institute of Physiologically Active Substances
Email: serkoviv@mail.ru
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
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