A Translational Model of Chronic Heart Failure
- 作者: Kryzhanovskii S.1, Tsorin I.1, Stolyaruk V.1, Vititnova M.1, Ionova E.1, Barchukov V.1, Miroshkina I.1, Sorokina A.1, Kozhevnikova L.1, Durnev A.1
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隶属关系:
- V. V. Zakusov Research Institute of Pharmacology
- 期: 卷 167, 编号 5 (2019)
- 页面: 706-710
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242051
- DOI: https://doi.org/10.1007/s10517-019-04604-y
- ID: 242051
如何引用文章
详细
We created a translational model of chronic heart failure in rats that developed in 3 months after reproducing experimental anterior transmural myocardial infarction. The model simulated the basic clinicodiagnostic criteria of this disease: impaired contractility and dilatation of heart ventricles, signs of venous congestion, elevated plasma content of biochemical markers, and abnormal overexpression of AT1aR and β-adrenoceptors.
作者简介
S. Kryzhanovskii
V. V. Zakusov Research Institute of Pharmacology
编辑信件的主要联系方式.
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
I. Tsorin
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
V. Stolyaruk
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
M. Vititnova
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
E. Ionova
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
V. Barchukov
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
I. Miroshkina
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
A. Sorokina
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
L. Kozhevnikova
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
A. Durnev
V. V. Zakusov Research Institute of Pharmacology
Email: sak_538@yandex.ru
俄罗斯联邦, Moscow
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