Reaction of Mast Cells in the Zone of Polypropylene Mesh Implantation
- 作者: Grigoryuk A.1, Belov S.2, Kotsyuba A.1
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隶属关系:
- Pacific State Medical University
- Primorye Territorial Tuberculosis Control Center
- 期: 卷 167, 编号 5 (2019)
- 页面: 694-697
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242029
- DOI: https://doi.org/10.1007/s10517-019-04601-1
- ID: 242029
如何引用文章
详细
Reaction of mast cells of adult male Wistar rats (n=15) in the zone of polypropylene mesh fixation was studied by histochemical, immunohistochemical, and traditional morphological methods on days 1, 5, 10, and 30 after implantation. Immediately after the intervention, mast cells stimulated the processes aimed at wound healing. Secretion of mast cells was clearly regulatory. These cells migrated to the zone of injury for subsequent activation of their function. The number of cNOS+ mast cells near the polypropylene mesh was maximum on day 1 and the number of iNOS+ mast cells peaked on day 5 of the experiment, which probably represented a compensatory reaction. Presumably, stimulation of fibrillogenesis was largely due to the activatory effect of mast cells on the fibroblast function, but not to collagen production by these mast cells.
作者简介
A. Grigoryuk
Pacific State Medical University
编辑信件的主要联系方式.
Email: aa_grig@mail.ru
俄罗斯联邦, Vladivostok
S. Belov
Primorye Territorial Tuberculosis Control Center
Email: aa_grig@mail.ru
俄罗斯联邦, Vladivostok
A. Kotsyuba
Pacific State Medical University
Email: aa_grig@mail.ru
俄罗斯联邦, Vladivostok