Reaction of Mast Cells in the Zone of Polypropylene Mesh Implantation
- Авторы: Grigoryuk A.1, Belov S.2, Kotsyuba A.1
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Учреждения:
- Pacific State Medical University
- Primorye Territorial Tuberculosis Control Center
- Выпуск: Том 167, № 5 (2019)
- Страницы: 694-697
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242029
- DOI: https://doi.org/10.1007/s10517-019-04601-1
- ID: 242029
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Аннотация
Reaction of mast cells of adult male Wistar rats (n=15) in the zone of polypropylene mesh fixation was studied by histochemical, immunohistochemical, and traditional morphological methods on days 1, 5, 10, and 30 after implantation. Immediately after the intervention, mast cells stimulated the processes aimed at wound healing. Secretion of mast cells was clearly regulatory. These cells migrated to the zone of injury for subsequent activation of their function. The number of cNOS+ mast cells near the polypropylene mesh was maximum on day 1 and the number of iNOS+ mast cells peaked on day 5 of the experiment, which probably represented a compensatory reaction. Presumably, stimulation of fibrillogenesis was largely due to the activatory effect of mast cells on the fibroblast function, but not to collagen production by these mast cells.
Об авторах
A. Grigoryuk
Pacific State Medical University
Автор, ответственный за переписку.
Email: aa_grig@mail.ru
Россия, Vladivostok
S. Belov
Primorye Territorial Tuberculosis Control Center
Email: aa_grig@mail.ru
Россия, Vladivostok
A. Kotsyuba
Pacific State Medical University
Email: aa_grig@mail.ru
Россия, Vladivostok
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