Combined Effect of Bone Morphogenetic Protein-2 and Erythropoietin on Regeneration of Cranial Bone Defects in Mice


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

Using mouse model of regeneration of critical size cranial defects, we studied combined effect of 1 and 10 μg of BMP-2 of prokaryotic origin and recombinant erythropoietin (Epostim) injected subcutaneously in the area of bone defect in a total dose of 6000 U/kg. Erythropoietin considerably improved quantitative and qualitative characteristics of the bone tissue in the site of implantation when used in combination with BMP-2 in both concentrations.

作者简介

A. Gromov

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

M. Bartov

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

P. Orlova

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

V. Manskikh

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; A. N. Belozersky Research Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow; Moscow

M. Krivozubov

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

T. Grunina

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

M. Manukhina

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

N. Strukova

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

K. Nikitin

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow

V. Lunin

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; All-Russian Research Institute of Agricultural Biotechnology

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow; Moscow

A. Karyagina

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; A. N. Belozersky Research Institute of Physico-Chemical Biology, M. V. Lomonosov Moscow State University; All-Russian Research Institute of Agricultural Biotechnology

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow; Moscow; Moscow

A. Gintsburg

N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation

Email: alexander.v.gromov@gmail.com
俄罗斯联邦, Moscow


版权所有 © Springer Science+Business Media, LLC, part of Springer Nature, 2019
##common.cookie##