Age-Dependent Effects of NO on Rhythmic Activity of Postganglionic Sympathetic Fibers
- 作者: Moiseev K.1, Verbovetskaya A.1, Maslyukov A.1, Maslyukov P.1
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隶属关系:
- Yaroslavl State Medical University, Ministry of Health of the Russian Federation
- 期: 卷 167, 编号 2 (2019)
- 页面: 191-193
- 栏目: Physiology
- URL: https://journals.rcsi.science/0007-4888/article/view/241576
- DOI: https://doi.org/10.1007/s10517-019-04488-y
- ID: 241576
如何引用文章
详细
We studied the effects of exogenous NO donor (sodium nitroprusside) and NO synthesis blocker (100 μM L-NAME) on baseline electrical activity of postganglionic fibers in the sympathetic superior cervical in rats during postnatal ontogeny. Starting the age of 20 days, sodium nitroprusside increased the mean discharge amplitude and the spectrum power in the respiratory (0.7-1.5 Hz) and cardiac (4-7 Hz) frequency bands. In contrast, application of L-NAME for 1 h decreased the spectrum power in these bands. Both agents produced no significant effect on the rhythmic sympathetic discharges at frequencies >8 Hz.
作者简介
K. Moiseev
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
俄罗斯联邦, Yaroslavl
A. Verbovetskaya
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
俄罗斯联邦, Yaroslavl
A. Maslyukov
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
俄罗斯联邦, Yaroslavl
P. Maslyukov
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: mpm@ysmu.ru
俄罗斯联邦, Yaroslavl