Age-Dependent Effects of NO on Rhythmic Activity of Postganglionic Sympathetic Fibers
- Авторы: Moiseev K.1, Verbovetskaya A.1, Maslyukov A.1, Maslyukov P.1
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Учреждения:
- Yaroslavl State Medical University, Ministry of Health of the Russian Federation
- Выпуск: Том 167, № 2 (2019)
- Страницы: 191-193
- Раздел: Physiology
- URL: https://journals.rcsi.science/0007-4888/article/view/241576
- DOI: https://doi.org/10.1007/s10517-019-04488-y
- ID: 241576
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Аннотация
We studied the effects of exogenous NO donor (sodium nitroprusside) and NO synthesis blocker (100 μM L-NAME) on baseline electrical activity of postganglionic fibers in the sympathetic superior cervical in rats during postnatal ontogeny. Starting the age of 20 days, sodium nitroprusside increased the mean discharge amplitude and the spectrum power in the respiratory (0.7-1.5 Hz) and cardiac (4-7 Hz) frequency bands. In contrast, application of L-NAME for 1 h decreased the spectrum power in these bands. Both agents produced no significant effect on the rhythmic sympathetic discharges at frequencies >8 Hz.
Об авторах
K. Moiseev
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
Россия, Yaroslavl
A. Verbovetskaya
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
Россия, Yaroslavl
A. Maslyukov
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
Россия, Yaroslavl
P. Maslyukov
Yaroslavl State Medical University, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: mpm@ysmu.ru
Россия, Yaroslavl