Discoordination of Autonomic Support of Functions in the Pathogenesis Gastroesophageal Reflux Disease


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A cross-sectional study performed on a continuous sample of 32 patients (mean age 46.36±3.31 years) with gastroesophageal reflux disease and excess body weight showed that the disturbance of sympathetic/parasympathetic relationships, disruption of segmental and compensatory increase in the suprasegmental mechanisms of autonomic regulation determines the course of gastroesophageal reflux disease in these patients.

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S. Kseneva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences

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Email: viksbest@mail.ru
俄罗斯联邦, Tomsk

E. Borodulina

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences

Email: viksbest@mail.ru
俄罗斯联邦, Tomsk

V. Udut

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; National Research Tomsk State University

Email: viksbest@mail.ru
俄罗斯联邦, Tomsk; Tomsk


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