Discoordination of Autonomic Support of Functions in the Pathogenesis Gastroesophageal Reflux Disease


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Abstract

A cross-sectional study performed on a continuous sample of 32 patients (mean age 46.36±3.31 years) with gastroesophageal reflux disease and excess body weight showed that the disturbance of sympathetic/parasympathetic relationships, disruption of segmental and compensatory increase in the suprasegmental mechanisms of autonomic regulation determines the course of gastroesophageal reflux disease in these patients.

About the authors

S. I. Kseneva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences

Author for correspondence.
Email: viksbest@mail.ru
Russian Federation, Tomsk

E. V. Borodulina

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences

Email: viksbest@mail.ru
Russian Federation, Tomsk

V. V. Udut

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences; National Research Tomsk State University

Email: viksbest@mail.ru
Russian Federation, Tomsk; Tomsk


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