Blood Serum Levels of Proinflammatory Cytokines (IL-1β, IL-6, TNFα, IL-8, IL-12p70, and IFNγ) in Patients with Uterine Myoma
- 作者: Konenkov V.1, Koroleva E.1, Orlov N.1, Prokof’ev V.1, Shevchenko A.1, Novikov A.1, Dergacheva T.1
-
隶属关系:
- Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- 期: 卷 165, 编号 5 (2018)
- 页面: 698-701
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240692
- DOI: https://doi.org/10.1007/s10517-018-4245-0
- ID: 240692
如何引用文章
详细
We analyzed cytokine profile in blood serum of patients with uterine myoma and revealed significantly reduced level of IFNγ and a tendency towards a decrease in the levels of IL-1β and TNFα; the levels of IL-6, IL-8, and IL-12p70 did not differ from those in healthy women. The drop in the concentrations of factors responsible for inflammation and angiogenesis in tissues are unfavorable for proliferation and differentiation of the uterine tissues.
作者简介
V. Konenkov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
E. Koroleva
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
N. Orlov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
V. Prokof’ev
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
A. Shevchenko
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
A. Novikov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
T. Dergacheva
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: dr-tanja@yandex.ru
俄罗斯联邦, Novosibirsk
![](/img/style/loading.gif)