Blood Serum Levels of Proinflammatory Cytokines (IL-1β, IL-6, TNFα, IL-8, IL-12p70, and IFNγ) in Patients with Uterine Myoma
- Авторы: Konenkov V.1, Koroleva E.1, Orlov N.1, Prokof’ev V.1, Shevchenko A.1, Novikov A.1, Dergacheva T.1
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Учреждения:
- Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Выпуск: Том 165, № 5 (2018)
- Страницы: 698-701
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240692
- DOI: https://doi.org/10.1007/s10517-018-4245-0
- ID: 240692
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Аннотация
We analyzed cytokine profile in blood serum of patients with uterine myoma and revealed significantly reduced level of IFNγ and a tendency towards a decrease in the levels of IL-1β and TNFα; the levels of IL-6, IL-8, and IL-12p70 did not differ from those in healthy women. The drop in the concentrations of factors responsible for inflammation and angiogenesis in tissues are unfavorable for proliferation and differentiation of the uterine tissues.
Об авторах
V. Konenkov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
E. Koroleva
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
N. Orlov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
V. Prokof’ev
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
A. Shevchenko
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
A. Novikov
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
T. Dergacheva
Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: dr-tanja@yandex.ru
Россия, Novosibirsk
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