Specific Features of Depolarization of the Left and Right Atria in Rats with Alcoholic Cardiomyopathy

I. M. Roshchevskaya; S. L. Smirnova; I. B. Tsorin; V. N. Stolyaruk; A. V. Nadorova; M. B. Vititnova; L. G. Kolik; S. A. Kryzhanovskii

doi:10.1007/s10517-018-4226-3

Specific Features of Depolarization of the Left and Right Atria in Rats with Alcoholic Cardiomyopathy

作者: Roshchevskaya I.¹, Smirnova S.¹, Tsorin I.², Stolyaruk V.², Nadorova A.², Vititnova M.², Kolik L.², Kryzhanovskii S.²
隶属关系:
1. Department of Comparative Cardiology, Komi Research Center, Ural Division of the Russian Academy of Sciences
2. V. V. Zakusov Research Institute of Pharmacology
期: 卷 165, 编号 5 (2018)
页面: 617-620
栏目: Article
URL: https://journals.rcsi.science/0007-4888/article/view/240602
DOI: https://doi.org/10.1007/s10517-018-4226-3
ID: 240602

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Using a translation model of alcoholic cardiomyopathy in rats we showed the presence of an additional abnormal excitation focus in the area of the pulmonary vein lacunae in the left atrium and enhanced heterogeneity of the atrium depolarization pattern. These changes can determine electric instability of the myocardium and induce malignant heart rhythm disturbances including, sudden cardiac death.