Specific Features of Depolarization of the Left and Right Atria in Rats with Alcoholic Cardiomyopathy
- Autores: Roshchevskaya I.1, Smirnova S.1, Tsorin I.2, Stolyaruk V.2, Nadorova A.2, Vititnova M.2, Kolik L.2, Kryzhanovskii S.2
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Afiliações:
- Department of Comparative Cardiology, Komi Research Center, Ural Division of the Russian Academy of Sciences
- V. V. Zakusov Research Institute of Pharmacology
- Edição: Volume 165, Nº 5 (2018)
- Páginas: 617-620
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240602
- DOI: https://doi.org/10.1007/s10517-018-4226-3
- ID: 240602
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Resumo
Using a translation model of alcoholic cardiomyopathy in rats we showed the presence of an additional abnormal excitation focus in the area of the pulmonary vein lacunae in the left atrium and enhanced heterogeneity of the atrium depolarization pattern. These changes can determine electric instability of the myocardium and induce malignant heart rhythm disturbances including, sudden cardiac death.
Sobre autores
I. Roshchevskaya
Department of Comparative Cardiology, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: SAK-538@yandex.ru
Rússia, Syktyvkar, Komi Republic
S. Smirnova
Department of Comparative Cardiology, Komi Research Center, Ural Division of the Russian Academy of Sciences
Email: SAK-538@yandex.ru
Rússia, Syktyvkar, Komi Republic
I. Tsorin
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
Rússia, Moscow
V. Stolyaruk
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
Rússia, Moscow
A. Nadorova
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
Rússia, Moscow
M. Vititnova
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
Rússia, Moscow
L. Kolik
V. V. Zakusov Research Institute of Pharmacology
Email: SAK-538@yandex.ru
Rússia, Moscow
S. Kryzhanovskii
V. V. Zakusov Research Institute of Pharmacology
Autor responsável pela correspondência
Email: SAK-538@yandex.ru
Rússia, Moscow
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