Effect of GRP119 Receptor Agonist, Compound MBX-2982, on Activity of Human Glucokinase


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Validation of the method for studies of glucokinase activators by the spectrophotometric method in an in vitro test system is carried out. The advantage of NAD coenzyme vs. thio-NAD is proven. Manifest activation of glucokinase by MBX-2982 compound (GPR119 agonist) in a wide range of concentrations is demonstrated experimentally.

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A. Spasov

Volgograd State Medical University, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: aspasov@mail.ru
俄罗斯联邦, Volgograd

V. Kosolapov

Volgograd State Medical University, Ministry of Health of the Russian Federation

Email: aspasov@mail.ru
俄罗斯联邦, Volgograd

D. Babkov

Volgograd State Medical University, Ministry of Health of the Russian Federation

Email: aspasov@mail.ru
俄罗斯联邦, Volgograd

O. Maika

Volgograd State Medical University, Ministry of Health of the Russian Federation

Email: aspasov@mail.ru
俄罗斯联邦, Volgograd


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