Enviar artigo por via de e-mail Effect of GRP119 Receptor Agonist, Compound MBX-2982, on Activity of Human Glucokinase
- Autores: Spasov A.1, Kosolapov V.1, Babkov D.1, Maika O.1
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Afiliações:
- Volgograd State Medical University, Ministry of Health of the Russian Federation
- Edição: Volume 163, Nº 5 (2017)
- Páginas: 695-698
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239198
- DOI: https://doi.org/10.1007/s10517-017-3881-0
- ID: 239198
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Resumo
Validation of the method for studies of glucokinase activators by the spectrophotometric method in an in vitro test system is carried out. The advantage of NAD coenzyme vs. thio-NAD is proven. Manifest activation of glucokinase by MBX-2982 compound (GPR119 agonist) in a wide range of concentrations is demonstrated experimentally.
Sobre autores
A. Spasov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: aspasov@mail.ru
Rússia, Volgograd
V. Kosolapov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: aspasov@mail.ru
Rússia, Volgograd
D. Babkov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: aspasov@mail.ru
Rússia, Volgograd
O. Maika
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: aspasov@mail.ru
Rússia, Volgograd
