Effects of Physiological Nitric Oxide Donor on Oxidative Metabolism in Rat Blood
- 作者: Martusevich A.1,2, Davydyuk A.2, Martusevich A.3, Kovaleva L.2
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隶属关系:
- Volga Region Federal Medical Research Center, Ministry of Health of the Russian Federation
- Kirov State Medical University, Ministry of Health of the Russian Federation
- N. I. Lobachevsky Nizhny Novgorod National Research State University
- 期: 卷 163, 编号 5 (2017)
- 页面: 602-604
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239116
- DOI: https://doi.org/10.1007/s10517-017-3858-z
- ID: 239116
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详细
The effects of exogenous dinitrosyl iron complexes with glutathione ligands on the parameters of oxidative metabolism in the rat blood are studied. The intensity of LPO, total antioxidant activity, and MDA level in the plasma are compared in rats receiving intraperitoneal injections of saline without and with dinitrosyl iron complexes in various concentrations (0.15, 0.30, 0.45, and 0.60 mM). Glutathione—containing dinitrosyl iron complexes are characterized by antioxidant effect that non-linearly depended of the dose with optimum at 0.30-0.45 mM.
作者简介
A. Martusevich
Volga Region Federal Medical Research Center, Ministry of Health of the Russian Federation; Kirov State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: cryst-mart@yandex.ru
俄罗斯联邦, Nizhny Novgorod; Kirov
A. Davydyuk
Kirov State Medical University, Ministry of Health of the Russian Federation
Email: cryst-mart@yandex.ru
俄罗斯联邦, Kirov
A. Martusevich
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: cryst-mart@yandex.ru
俄罗斯联邦, Nizhny Novgorod
L. Kovaleva
Kirov State Medical University, Ministry of Health of the Russian Federation
Email: cryst-mart@yandex.ru
俄罗斯联邦, Kirov