Отправить статью по E-mail Effects of Physiological Nitric Oxide Donor on Oxidative Metabolism in Rat Blood
- Авторы: Martusevich A.K.1,2, Davydyuk A.V.2, Martusevich A.A.3, Kovaleva L.K.2
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Учреждения:
- Volga Region Federal Medical Research Center, Ministry of Health of the Russian Federation
- Kirov State Medical University, Ministry of Health of the Russian Federation
- N. I. Lobachevsky Nizhny Novgorod National Research State University
- Выпуск: Том 163, № 5 (2017)
- Страницы: 602-604
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239116
- DOI: https://doi.org/10.1007/s10517-017-3858-z
- ID: 239116
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Аннотация
The effects of exogenous dinitrosyl iron complexes with glutathione ligands on the parameters of oxidative metabolism in the rat blood are studied. The intensity of LPO, total antioxidant activity, and MDA level in the plasma are compared in rats receiving intraperitoneal injections of saline without and with dinitrosyl iron complexes in various concentrations (0.15, 0.30, 0.45, and 0.60 mM). Glutathione—containing dinitrosyl iron complexes are characterized by antioxidant effect that non-linearly depended of the dose with optimum at 0.30-0.45 mM.
Об авторах
A. Martusevich
Volga Region Federal Medical Research Center, Ministry of Health of the Russian Federation; Kirov State Medical University, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: cryst-mart@yandex.ru
Россия, Nizhny Novgorod; Kirov
A. Davydyuk
Kirov State Medical University, Ministry of Health of the Russian Federation
Email: cryst-mart@yandex.ru
Россия, Kirov
A. Martusevich
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: cryst-mart@yandex.ru
Россия, Nizhny Novgorod
L. Kovaleva
Kirov State Medical University, Ministry of Health of the Russian Federation
Email: cryst-mart@yandex.ru
Россия, Kirov
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