Nephroprotective Effect of EDL Peptide at Acute Injury of Kidneys of Different Genesis
- 作者: Zamorskii I.1, Shchudrova T.1, Lin’kova N.2,3, Nichik T.2, Khavinson V.2,4
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隶属关系:
- Bukovinian State Medical University
- St. Petersburg Institute of Bioregulation and Gerontology
- Peter the Great St. Petersburg Polytechnic University
- I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
- 期: 卷 163, 编号 3 (2017)
- 页面: 389-393
- 栏目: Biogerontology
- URL: https://journals.rcsi.science/0007-4888/article/view/238930
- DOI: https://doi.org/10.1007/s10517-017-3811-1
- ID: 238930
如何引用文章
详细
EDL peptide produced a nephroprotective effect on experimental models gentamycin-induced nephropathy and ischemia/reperfusion kidney injury in rats. The nephroprotective effect of EDL peptide manifested in prevention of oliguria and retention azotemia, a decrease in proteinuria and sodium excretion, prevention of critical decrease in activities of antioxidant enzymes, suppression of LPO, and normalization of energy supply to kidneys cells. Our findings confirm the prospects of further studies of the nephroprotective properties of peptide EDL in various pathologies of the kidneys.
作者简介
I. Zamorskii
Bukovinian State Medical University
Email: miayy@yandex.ru
乌克兰, Chernivtsi
T. Shchudrova
Bukovinian State Medical University
Email: miayy@yandex.ru
乌克兰, Chernivtsi
N. Lin’kova
St. Petersburg Institute of Bioregulation and Gerontology; Peter the Great St. Petersburg Polytechnic University
编辑信件的主要联系方式.
Email: miayy@yandex.ru
俄罗斯联邦, St. Petersburg; St. Petersburg
T. Nichik
St. Petersburg Institute of Bioregulation and Gerontology
Email: miayy@yandex.ru
俄罗斯联邦, St. Petersburg
V. Khavinson
St. Petersburg Institute of Bioregulation and Gerontology; I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Email: miayy@yandex.ru
俄罗斯联邦, St. Petersburg; St. Petersburg
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