Study of Proliferative Activity of Vaginal Epithelium in Women with Stress Urinary Incontinence Treated by Er:YAG Laser
- 作者: Lapii G.1, Yakovleva A.1, Neimark A.2, Lushnikova E.1
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隶属关系:
- Institute of Molecular Pathology and Pathomorphology
- Altai State Medical University
- 期: 卷 163, 编号 2 (2017)
- 页面: 280-283
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238818
- DOI: https://doi.org/10.1007/s10517-017-3784-0
- ID: 238818
如何引用文章
详细
The expression of Ki-67 proliferation marker was studied in vaginal biopsy specimens from women with stress urinary incontinence treated using a Fotona nonablative erbium laser. Cells expressing Ki-67 were located in all cases in the parabasal and basal levels of stratified squamous epithelium, the index of labeled nuclei before Er:YAG laser exposure was 19.05±2.86%. After 1-2 months of laser therapy, the index of labeled nuclei in the epithelium increased significantly and reached 31.79±2.25%. These changes were interpreted as a result of epithelial-stromal interactions. Presumably, the increase in proliferative activity of the vaginal epithelium after exposure to Er:YAG laser was due to the presence of an appreciable level of synthetically active fibroblasts in the subepithelial stroma.
作者简介
G. Lapii
Institute of Molecular Pathology and Pathomorphology
编辑信件的主要联系方式.
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
A. Yakovleva
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
A. Neimark
Altai State Medical University
Email: pathol@inbox.ru
俄罗斯联邦, Barnaul
E. Lushnikova
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Novosibirsk
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