Immunogenesis in White Mice Infected with Yersinia pestis with Different Plasmid Composition
- 作者: Balakhonov S.1, Vityazeva S.1, Dubrovina V.1, Starovoitova T.1, Mukhturgin G.1, Ivanova T.1, Korytov K.1, Kolesnikov S.2
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隶属关系:
- Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
- Research Center of Family Health Problems and Human Reproduction
- 期: 卷 162, 编号 4 (2017)
- 页面: 470-473
- 栏目: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/238307
- DOI: https://doi.org/10.1007/s10517-017-3642-0
- ID: 238307
如何引用文章
详细
Morphological changes in the immunocompetent organs of white mice with experimental plague infection manifested in activation of the immune response of different degree and pathological process of different severity that depended on the plasmid composition of Y. pestis. Widening of the T-dependent zones in the immune organs of white mice infected with isogenic strains of Y. pestis with different plasmid composition attests to activation of cellular immunity. Our findings allow considering Y. pestis subsp. altaica I-2948/3, Y. pestis subsp. pestis I-3479 and Y. pestis subsp. pestis I-3480 as promising candidates for vaccine strains.
作者简介
S. Balakhonov
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
S. Vityazeva
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
V. Dubrovina
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
编辑信件的主要联系方式.
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
T. Starovoitova
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
G. Mukhturgin
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
T. Ivanova
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
K. Korytov
Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
S. Kolesnikov
Research Center of Family Health Problems and Human Reproduction
Email: dubrovina-valya@mail.ru
俄罗斯联邦, Irkutsk
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