Immunogenesis in White Mice Infected with Yersinia pestis with Different Plasmid Composition


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Рұқсат жабық Тек жазылушылар үшін

Аннотация

Morphological changes in the immunocompetent organs of white mice with experimental plague infection manifested in activation of the immune response of different degree and pathological process of different severity that depended on the plasmid composition of Y. pestis. Widening of the T-dependent zones in the immune organs of white mice infected with isogenic strains of Y. pestis with different plasmid composition attests to activation of cellular immunity. Our findings allow considering Y. pestis subsp. altaica I-2948/3, Y. pestis subsp. pestis I-3479 and Y. pestis subsp. pestis I-3480 as promising candidates for vaccine strains.

Авторлар туралы

S. Balakhonov

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

S. Vityazeva

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

V. Dubrovina

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Хат алмасуға жауапты Автор.
Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

T. Starovoitova

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

G. Mukhturgin

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

T. Ivanova

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

K. Korytov

Irkutsk Antiplague Research Institute of Siberia and Far East of Federal Service on Supervision in the Sphere of Consumers’ Rights Protection and Human Welfare

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk

S. Kolesnikov

Research Center of Family Health Problems and Human Reproduction

Email: dubrovina-valya@mail.ru
Ресей, Irkutsk


© Springer Science+Business Media New York, 2017

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