Nitrogen Oxide, Endothelin-1, and Serotonin in the Blood of Immature Spontaneously Hypertensive Rats
- 作者: Chibireva M.1, Aflyatumova G.2, Matveeva V.1, Bilalova D.1, Kuz’mina O.1, Sadykova D.2, Nigmatullina R.1
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隶属关系:
- Kazan State Medical University, Ministry of Health of the Russian Federation
- Kazan State Medical Academy, Ministry of Health of the Russian Federation
- 期: 卷 162, 编号 3 (2017)
- 页面: 310-312
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238153
- DOI: https://doi.org/10.1007/s10517-017-3602-8
- ID: 238153
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详细
Endothelial function is an early and sensitive marker of subclinical increase of BP in children and adolescents. It is associated with an imbalance of the key vasoactive factors (NO, endothelin-1, and serotonin). Immature spontaneously hypertensive rats (SHR line) are characterized by increased plasma concentrations of NO and endothelin-1 (by 14.7% and 2.9 times, respectively) and increased serotonin content in the plasma and platelets (by 2.7 and 2.3 times, respectively) in comparison with Wistar-Kyoto rats. Platelet count in the blood of SHR rats is by 50% higher than in Wistar-Kyoto rats.
作者简介
M. Chibireva
Kazan State Medical University, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan
G. Aflyatumova
Kazan State Medical Academy, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan, Tatarstan Republic
V. Matveeva
Kazan State Medical University, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan
D. Bilalova
Kazan State Medical University, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan
O. Kuz’mina
Kazan State Medical University, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan
D. Sadykova
Kazan State Medical Academy, Ministry of Health of the Russian Federation
Email: razinar@mail.ru
俄罗斯联邦, Kazan, Tatarstan Republic
R. Nigmatullina
Kazan State Medical University, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: razinar@mail.ru
俄罗斯联邦, Kazan
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